Spike in Cholera Deaths in Africa Inspires Need for Indigenous Vaccine Production

ZAMBIA – The 2025 Cholera deaths in Africa account for 99% of all reported cases. On Wednesday, in a virtual cholera conference held during the Africa emergency high-level meeting for heads of state organized by the Africa Centers for Disease Control and Prevention (Africa CDC), the African leaders stressed the need for an indigenous cholera vaccine production, to curb the growing concern.

Zambian President Hakainde Hichilema said there was a need for the continent to accelerate local vaccine and critical supply manufacturing while prioritizing domestic financing to reduce its reliance on unpredictable donor support.

“Since cholera knows no borders, we must strengthen cross-border coordination through joint surveillance, early warning systems and harmonized reporting mechanisms among neighboring states,” the global and African cholera champion wrote on Facebook after the meeting,

Angola’s President Joao Lourenco, who is the African Union (AU) chairperson, said cholera was much more than a health emergency, and it represented a major obstacle to economic, social and human development in Africa.

World Health Organization (WHO) Director General Tedros Ghebreyesus said in 2025, Africa has reported two-thirds of all cholera cases globally and 99% of all cholera-related deaths.

“Through the ICG (International Coordinating Group), we have delivered 230 million doses of oral cholera vaccines to 31 countries. We have also deployed emergency medical teams to 18 countries,” he said. “We need to expand local manufacturing of oral cholera vaccines and optimize the use of existing supplies through earlier detection and more efficient vaccination campaigns.”

The meeting was attended by the leaders of Angola, Zambia, Namibia, Malawi and the Democratic Republic of Congo.

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